Form 4 Tracker
Spyre Therapeutics, Inc.
SYRE

11 insider filings · Latest: May 8, 2026

Common Stock Transactions
Txn DateAcceptedInsiderTypeSharesAvg PriceValueShares OwnedFiling
May 8, 2026May 9 1:31 AMMichael Thomas HendersonDirector
Sale
80,000$74.40$6.0M88,606(D)

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May 8, 2026May 8 8:22 PMMICHAEL HENDERSON
Proposed Sale
80,000$73.10$5.8M

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May 1, 2026May 2 1:35 AMScott L BurrowsChief Financial Officer
Sale
12,500$71.37$892.1K97,994(D)

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May 1, 2026May 2 1:34 AMSheldon SloanChief Medical Officer
Sale
78,333$71.50$5.6M0(D)

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May 1, 2026May 2 1:34 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$71.37$1.1M612,540(D)

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May 1, 2026May 1 8:44 PMSHELDON SLOAN
Proposed Sale
78,333$74.45$5.8M

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May 1, 2026May 1 8:44 PMSCOTT BURROWS
Proposed Sale
27,500$74.45$2.0M

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Apr 1, 2026Apr 4 1:30 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$49.33$739.9K627,540(D)

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Apr 1, 2026Apr 4 1:30 AMSheldon SloanChief Medical Officer
Sale
7,958$50.00$397.9K0(D)

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Apr 1, 2026Apr 4 1:29 AMScott L BurrowsChief Financial Officer
Sale
7,500$49.34$370.1K97,994(D)

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Apr 1, 2026Apr 1 8:38 PMSHELDON SLOAN
Proposed Sale
7,958$50.44$401.4K

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Mar 3, 2026Mar 4 2:32 AMScott L BurrowsChief Financial Officer
Sale
2,500$40.65$101.6K97,994(D)

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Mar 2, 2026Mar 4 2:31 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$42.19$632.9K642,540(D)

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Mar 3, 2026Mar 3 9:43 PMSCOTT BURROWS
Proposed Sale
10,000$42.49$424.9K

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Mar 2, 2026Mar 2 9:31 PMCAMERON TURTLE
Proposed Sale
60,000$43.01$2.6M

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Feb 2, 2026Feb 5 2:33 AMCameron TurtleDirector, Chief Executive Officer
Sale
15,000$32.80$492.0K657,540(D)

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Nov 3, 2025Nov 3 9:24 PMCAMERON TURTLE
Proposed Sale
90,000$24.46$2.2M

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Oct 25, 2024Oct 25 8:28 PMSESSIONS, LLC
Proposed Sale
7,000$33.70$235.9K

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Stock Options & Derivatives
Txn DateAcceptedInsiderTypeSharesExercise PriceShares OwnedFiling
May 1, 2026May 2 1:35 AMScott L BurrowsChief Financial Officer
Option Exercise
12,500$14.50382,357(D)

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May 1, 2026May 2 1:34 AMSheldon SloanChief Medical Officer
Option Exercise
78,333$27.46321,667(D)

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Apr 1, 2026Apr 4 1:30 AMSheldon SloanChief Medical Officer
Option Exercise
7,958$21.6687,542(D)

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Apr 1, 2026Apr 4 1:29 AMScott L BurrowsChief Financial Officer
Option Exercise
7,500$14.50394,857(D)

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Mar 3, 2026Mar 4 2:32 AMScott L BurrowsChief Financial Officer
Option Exercise
2,500$14.50402,357(D)

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